ORIGINAL ARTICLE |
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Year : 2015 | Volume
: 3
| Issue : 1 | Page : 1-6 |
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Human immunodeficiency virus-positive women: Pregnancy, delivery outcomes, and complications at the Korle-Bu Teaching Hospital in Accra, Ghana
Joseph D Seffah1, RA Kwame-Aryee1, Richard M.K Adanu1, Lorna A Renner2, Margaret Lartey3
1 Department of Obstetrics and Gynaecology, University of Medical School, Accra, Ghana 2 Department of Child Health, University of Medical School, Accra, Ghana 3 Department of Medicine and Therapeutics, University of Medical School, Accra, Ghana
Correspondence Address:
Joseph D Seffah Department of Obstetrics and Gynaecology, University of Ghana Medical School, P. O. Box 4236, Accra Ghana
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/2321-9157.169178
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Objective: To study the delivery outcomes and complications associated with human immunodeficiency virus (HIV) positive women. Patients and Methods: A clinical audit from January 2006 to December 2009 involving patients accessing antenatal and delivery services at the Korle-Bu Teaching Hospital and using the voluntary counseling and testing/prevention of mother-to-child transmission services. Results:. HIV-positive women on the highly active antiretroviral therapy and ART prophylaxis had a mean CD4 count of 681 cells/ul (range: 412–810). Those who were not on any prophylaxis had a mean count of 288 cells/ul (range: 34–601). The study and comparison populations had similar mean ages; 29.8 years and 28.4 years, respectively (P = 0.09). About half the HIV-positive women had vaginal delivery though none had an episiotomy, forceps, or vacuum delivery. The HIV-positive women had a caesarean section rate of 55% and the rate in the HIV-negative women was 21% (P < 0.001). About 50% of the caesarean deliveries were done as emergencies. The mean birth weight was lower in the HIV-positive women; 2.9 kg versus 3.1 kg, respectively (P = 0.08). The perinatal losses were significantly higher in the study population; 95 versus 70 (P = 0.04). The mean placenta weight was smaller in the study population; 510 g versus 550 g (P = 0.04). Conclusion: Among the HIV-positive parturient, the caesarean delivery rate was about 50% and the neonatal outcomes were significantly worse than in the HIV-negative women. |
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