Other DME Gene Deletions
Gene | Phenotype | Genetic Background | Comments | Citation |
---|---|---|---|---|
GstP | None | 129xMF1 | Protection against DMBA toxicity | (28, 30) |
or | ||||
C57BL/6 | Protection against acetaminophen toxicity | |||
NQO-1 | None | 129xC57BL/6 | Increased menadione toxicity Myelogenous hyperplasia | (32) |
mEH | None | 129xC57BL/6 | Protection against DMBA toxicity | (34) |
sEH | Lowered systolic blood pressure (males) | 129xC57BL/6 | Altered renal arachidonic acid metabolism (males and females) | (35) |
GPx | None | 129xC57BL/6 | Increased sensitivity to Diquat | (36) |
GCLM | None | 129xC57BL/6 | Depleted GSH levels in liver, lung, pancreas and plasma | (40) |