Table of Contents

Reviews

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  • Roderic G. Eckenhoff

  PROMISCUOUS LIGANDS AND ATTRACTIVE CAVITIES: How do the inhaled anesthetics work?

  Mol Interv December 2001 1:258-268
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  Anesthesiology has been a subdiscipline of pharmacology for over a century. Still, the molecular mechanisms for induced unconsciousness remain open to debate.

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  • Zhigang Wang

  DNA DAMAGE-INDUCED MUTAGENESIS: A NOVEL TARGET FOR CANCER PREVENTION

  Mol Interv December 2001 1:269-281
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  A variety of lesser-known mammalian DNA polymerases function to prevent the shutdown of DNA replication. Can enzymes that "catalyze" mutation be targeted to prevent cancer?

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  • Jason C. Bermak and
  • Qun-Yong Zhou

  Accessory Proteins in the Biogenesis of G Protein-Coupled Receptors

  Mol Interv December 2001 1:282-287
  • Abstract
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  GPCRs remain the most pharmaceutically targeted cell membrane receptors. Accessory proteins that promote GPCR functionality and transport to the cell surface suggest that half the fun, indeed, may be in getting there.