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The enzymatic production and turnover of phosphoinositides provide a dynamic framework for cell signaling. Protein domains that function within this framework are crucial both to our understanding and therapeutic exploitation of cell signals.
The link between nerve injury and the development of neuropathic pain has yet to be understood in detail. The implication of dynorphin in the maintenance of neuropathic pain states is gaining attention and may hold the key to effective antinociceptive therapy.
Could the intravenous injection of naked DNA be a feasible route to gene therapy? Recent research into this question addresses whether the systemic administration of DNA could provide widespread expression of therapies genes.
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