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Hormone Replacement Therapy and Breast Cancer
Janet L. Stanford, PhD;
Noel S. Weiss, MD, DrPH
Arch Fam Med. 1996;5(6):349-350.
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IN THIS ISSUE of the ARCHIVES, Gambrell reviews the literature on the relationship between the use of menopausal hormones and breast cancer, which is a major concern for women considering hormone replacement therapy. In addition, the question of whether menopausal hormones should be prescribed for women who have been diagnosed as having breast cancer is raised.
Breast cancer is the leading cause of cancer incidence and the second leading cause of cancer deaths in American women.1 During her lifetime, a woman has about a 12% probability of developing and a 4% probability of dying of breast cancer.2 According to the most recent national data, the age-adjusted incidence of invasive breast cancer peaked in 1987 (112 per 100 000 women) and has remained stable through 199 1.2 Mortality also has been stable at about 27 per 100 000 women per year since 1984. These temporal trends have been
. . . [Full Text PDF of this Article]
Author Affiliations
Program in Epidemiology Division of Public Health Sciences Fred Hutchinson Cancer Research Center Department of Epidemiology School of Public Health and Community Medicine University of Washington Seattle
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