Bound to Be Different: Neurotransmitter Transporters Meet Their Bacterial Cousins

  Figure 1.
Figure 1.

Cl binding site in hSERT. Illustration depicts hSERT labeled helices (TM) and residue side chains identified by Forrest et al. (1) to coordinate Cl binding in the human serotonin transporter (hSERT) (stick rendering). The Cl (red) and Na+ (blue) ions are shown as labeled spheres. The figure was generated in Pymol (DeLano Scientific LLC, San Carlos,. California) using coordinates from a LeuTAa-hSERT homology model we have developed in our studies.

This Article

  1. MI December 2007 vol. 7 no. 6 306-309