Mechanism of Tissue-Selective Drug Action in the Cardiovascular System

  Figure 4.
Figure 4.

Physiological basis of corpora cavernosa smooth muscle relaxation. The NO–cGMP–protein kinase G cascade in the mechanism of penile erection is indicated. The role of PDE5 inhibition as a therapeutic target in ED is also indicated. [Modified with permission from International Education Initiative on Erectile Function Core Slide Kit, copyright Physicians World GmbH (2002).]

This Article

  1. MI April 2005 vol. 5 no. 2 84-93