Arch Fam Med
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  Vol. 3 No. 10, October 1994 TABLE OF CONTENTS
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Decline of Serum Cobalamin Levels With Increasing Age Among Geriatric Outpatients

Yulin Yao, MD; Grace Lu-Yao, MPH, PhD; David N. Mesches, MD; Wendy Lou, MD

Arch Fam Med. 1994;3(10):918-922.

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1. Allen RH. Megaloblastic anemia. In: Wyngaarden JB, Smith LH Jr, Bennett JC, eds. Cecil Textbook of Medicine. 19th ed. Philadelphia, Pa: WB Saunders Co; 1992:846-854.
2. Healton EB, Savage DG, Brust JCM, Garrett TJ, Lindenbaum J. Neurological aspects of cobalamin deficiency. Medicine. 1991;70:229-245. PUBMED
3. Martin DC, Francis J, Protetch J, Huff FJ. Time dependency of cognitive recovery with cobalamin replacement: report of a pilot study. J Am Geriatr Soc. 1992;40:168-172. PUBMED
4. Hitzhusen JC, Taplin ME, Stephenson WP, Ansell JE. Vitamin B12 levels and age. Am J Clin Pathol. 1986;85:32-36. PUBMED
5. Nilsson-Ehle H, Jagenburg R, Landahl S, Lindstedt S, Svanborg A, Westin J. Serum cobalamins in the elderly: a longitudinal study of a representative population sample from age 70-81. Eur J Haematol. 1991;47:10-16. PUBMED
6. Kolhouse JF, Kondo H, Allen NC, Podell E, Allen RH. Cobalamin analogues are present in human plasma and can mask cobalamin deficiency because current radioisotope dilution assays are not specific for true cobalamin. N Engl J Med. 1978;299:785-792. PUBMED
7. Allen RH, Stabler SP, Savage DG, Lindenbaum J. Diagnosis of cobalamin deficiency, I: usefulness of serum methylmalonic acid and total homocysteine concentrations. Am J Hematol. 1990;34:90-98. PUBMED
8. Lindenbaum J, Savage DG, Stabler SP, Allen RH. Diagnosis of cobalamin deficiency, II: relative sensitivities of serum cobalamin, methylmalonic acid, and total homocysteine concentrations. Am J Hematol. 1990;34:99-107. PUBMED
9. Herzlich B, Herbert V. Depletion of serum holotranscobalamin, II: an early sign of negative vitamin B12 balance. Lab Invest. 1986;58:332-337.
10. Pennypacker LC, Allen RH, Kelly JP, et al. High prevalence of cobalamin deficiency in elderly outpatients. J Am Geriatr Soc. 1992;40:1197-1204. PUBMED
11. Yao Y, Yao SL, Yao SS, Yao G, Lou W. Prevalence of vitamin B12 deficiency among geriatric outpatients. J Fam Pract. 1992;35:524-528. PUBMED
12. Stabler SP, Allen RH, Savage DG, Lindenbaum J. Clinical spectrum and diagnosis of cobalamin deficiency. Blood. 1990;76:871-881. FREE FULL TEXT
13. Barber KE, Christie ML, Thula R, Cutfield RG. Vitamin B12 concentrations in the elderly: a regional study. N Z Med J. 1989;102:406-408. PUBMED
14. Magnus EM, Bache-Wiig JE, Aanderson TR, Melbostad E. Folate and vitamin B-12 (cobalamin) blood levels in elderly persons in geriatric homes. Scand J Haematol. 1982;28:360-366. PUBMED
15. Lindenbaum J, Healton EB, Savage D, et al. Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med. 1988;318:1720-1728. PUBMED
16. Carmel R. Pernicious anemia: the expected findings of very low serum cobalamin levels, anemia, and macrocytosis are often lacking. Arch Intern Med. 1988;148:1712-1714. FREE FULL TEXT
17. Hector M, Burton J. What are the psychiatric manifestations of vitamin B-12 deficiency? J Am Geriatr Soc. 1988;36:1105-1112. PUBMED
18. Carmel R, Sinow RM, Siegel ME, Samloff IM. Food cobalamin malabsorption occurs frequently in patients with unexplained low serum cobalamin levels. Arch Intern Med. 1988;148:1715-1719. FREE FULL TEXT
19. Lederle FA. Oral cyanocobalamin for pernicious anemia: medicine's best kept secret? JAMA. 1991;265:94-95. FREE FULL TEXT
20. Hathcock JN, Troendle GJ. Oral cobalamin for treatment of pernicious anemia? JAMA. 1991;265:96-97. FREE FULL TEXT