Arch Fam Med
Institution: STANFORD Univ Med Center  | My Account | E-mail Alerts | Access Rights | Sign In
  Vol. 2 No. 4, April 1993 TABLE OF CONTENTS
  •  Online Features
  Brief Reports
 This Article
 •Full text PDF
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal

Carisoprodol as a Drug of Abuse

George S. Rust, MD, MPH; Robert Hatch, MD, MPH; John G. Gums, PharmD

Arch Fam Med. 1993;2(4):429-432.

Article references have been provided for searching and linking. Additional reference information may be available in the article PDF.

1. Soma (carisoprodol tablets). In: Physician's Desk Reference. 45th ed. Oradell, NJ: Medical Economics Books; 1991:2283.
2. Fraser HF, Essig CF, Wolbach AB. Evaluation of carisoprodol and phenyramidol for addictiveness. Bull Narc. 1961;13:1-5. PUBMED
3. Wyller TB, Korsmo G, Gadeholt G. Dependence on carisoprodol (Somadril): a prospective withdrawal study among prisoners [in Norwegian]. Tidsskr Nor Laegeforen. 1991;111:193-195. English abstract. PUBMED
4. Hollister LE. The prebenzodiazepine era. J Psychoactive Drugs. 1983;15:9-13. PUBMED
5. Luehr JG, Meyerle KA, Larson EW. Mail-order (veterinary) drug dependence. JAMA. 1990;263:657. FREE FULL TEXT
6. Morse RM, Chua L. Carisoprodol dependence: a case report. Am J Drug Alcohol Abuse. 1978;5:527-530. PUBMED
7. Elder NC. Abuse of skeletal muscle relaxants. Am Fam Physician. 1991;44:1223-1226. PUBMED
8. Today's drugs: carisoprodol. BMJ. 1964;5394:1363-1364.
9. Roszkowski AP. A pharmacological comparison of therapeutically useful centrally-acting skeletal muscle relaxants. J Pharmacol Exp Ther. 1970;129:75-81.
10. Berger FM, Kletzkin M, Ludwig BJ, Margolin S. Review of the pharmacology and efficacy of carisoprodol. Ann N Y Acad Sci. 1960;86:90-107. PUBMED
11. Cedarbaum JM, Schleifer LS. Drugs for Parkinson's disease, spasticity, and acute muscle spasms. In: Gilman AG, ed. Pharmacological Basis of Therapeutics. 8th ed. Elmsford, NY: Pergamon Press Inc; 1990:481-482.
12. Elenbaas JK. Centrally acting oral skeletal muscle relaxants. Am J Hosp Pharm. 1980;37:1313-1323. ABSTRACT
13. Douglas JF, Ludwig GJ, Schosser A. The metabolic fate of carisoprodol in the dog. J Pharm Exp Ther. 1962;138:21-27. FREE FULL TEXT
14. Meyer MC, Straughn AB. Meprobamate. J Am Pharm Assoc. 1977;17:173-175. PUBMED
15. Adams HR, Kerzee T, Morehead CD. Carisoprodol-related death in a child. J Forensic Sci. 1975;20:200-202. PUBMED
16. Kintz P, Mangin P, Lugnier AA, Chaumont AJ. A rapid and sensitive gas chromatographic analysis of meprobamate and carisoprodol in urine and plasma. J Anal Toxicol. 1988;12:73-74. PUBMED
17. Katz RL. Sedatives and tranquilizers. N Engl J Med. 1972;286:757-760. PUBMED
18. Nakamura H, Shimuzu M. Persistence of drug experience in rats formerly dependent on phenobarbital or meprobamate. Neuropharmacology. 1983;22:923-926. PUBMED
19. Yanagita T, Takahashi S. Dependence liability of several sedative-hypnotic agents evaluated in monkeys. J Pharmacol Exp Ther. 1973;185:307-316. FREE FULL TEXT
20. Nakamura H, Shimuzu M. Physical dependence on meprobamate after repeated oral administration in rats. Jpn J Pharmacol. 1983;33:1171-1176. PUBMED
21. Roache JD, Griffiths RR. Lorazepam and meprobamate dose effects in humans: behavioral effects and abuse liability. J Pharmacol Exp Ther. 1987;243:978-988. FREE FULL TEXT
22. Rall TW. Hypnotics and sedatives: meprobamate. In: Gilman AG, ed. Pharmacological Basis of Therapeutics. 8th ed. Elmsford, NY: Pergamon Press Inc; 1990:366-367.
23. Giannini AJ, Price WA, Giannini MC. Contemporary drugs of abuse. Am Fam Phys. 1986;33:207-216. PUBMED
24. Cowan IC, Mapes RE. Carisoprodol in the management of musculoskeletal disorders. Ann Phys Med. 1963;7:140-143.
25. Hindle TH. Comparison of carisoprodol, butabarbital, and placebo in treatment of the low back syndrome. Calif Med. 1972;117:7-11. PUBMED
26. Boyles WF, Glassman JM, Soyka JP. Management of acute musculoskeletal conditions: thoracolumbar strain or sprain. Today Ther Trends. 1983;1:1-16.
27. Baratta RR. A double-blind comparative study of carisoprodol, propoxyphene, and placebo in the management of low back syndrome. Curr Ther Res. 1976;20:233-240. PUBMED
28. Deyo RM. Conservative therapy for low back pain: distinguishing useful from useless therapy. JAMA. 1983;250:1057-1062. FREE FULL TEXT
29. Rolling HE, Glassman JM, Soyka JP. Management of acute musculoskeletal conditions: thoracolumbar strain or sprain: a double-blind evaluation comparing the efficacy and safety of carisoprodol with cyclobenzaprine hydrochloride. Curr Ther Res. 1983;34:917-927.
30. Miller AR. A comparative study of Parafon Forte tablets and Soma Compound in the treatment of painful skeletal muscle conditions. Curr Ther Res. 1976;19:444-450. PUBMED
31. Eddy NB, Friebel H, Hahn KJ, Halbach H. Codeine and its alternates for pain and cough relief: alternates for pain relief. Bull World Health Organ. 1969;40:1-53. PUBMED
32. Data From the Drug Abuse Warning Network (DAWN): Annual Emergency Room Data, 1990. Rockville, Md: National Institute on Drug Abuse; 1991. US Dept of Health and Human Services publication, series I, No. 10-A, p 34.
33. Data From the Drug Abuse Warning Network (DAWN): Annual Data, 1989. Rockville, Md: National Institute on Drug Abuse; 1990. US Dept of Health and Human Services, series I, No. 9, p 53.
34. Goldberg D. Carisoprodol toxicity. Milit Med. 1969;134:597-601.