Arch Fam Med
Institution: STANFORD Univ Med Center  | My Account | E-mail Alerts | Access Rights | Sign In
  Vol. 2 No. 11, November 1993 TABLE OF CONTENTS
  •  Online Features
 This Article
 •Full text PDF
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal

Tomorrow's Prenatal Genetic Testing

Should We Test for 'Minor' Diseases?

Carson Strong, PhD

Arch Fam Med. 1993;2(11):1187-1193.

Article references have been provided for searching and linking. Additional reference information may be available in the article PDF.

1. President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research. Screening and Counseling for Genetic Conditions. Washington, DC: Government Printing Office; 1983:37-38, 55, 58.
2. Juengst ET. Prenatal diagnosis and the ethics of uncertainty. In: Monagle J, Thomasma D, ed. Medical Ethics: A Guide for Health Professionals. Rockville, Md: Aspen Publishing Co; 1988:12-25.
3. Faden RR, Chwalow AJ, Quaid K, et al. Prenatal screening and pregnant women's attitudes toward the abortion of defective fetuses. Am J Public Health. 1987;77:288-290. FREE FULL TEXT
4. Evans MI, Drugan A, Bottoms SF, et al. Attitudes on the ethics of abortion, sex selection, and selective pregnancy termination among professionals, ethicists, and clergy likely to encounter such situations. Am J Obstet Gynecol. 1991;164:1092-1099. PUBMED
5. Botkin JR. Ethical issues in human genetic technology. Pediatrician. 1990;17:100-107. PUBMED
6. Wachbroit R. Making the grade: testing for human genetic disorders. Hofstra Law Rev. 1988;16:583-599.
7. Kan YW. Development of DNA analysis for human diseases: sickle cell anemia and thalassemia as a paradigm. JAMA. 1992;267:1532-1536. FREE FULL TEXT
8. Riordan JR, Rommens JM, Kerem B, et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science. 1989;245:1066-1073. FREE FULL TEXT
9. Koenig M, Hoffman EP, Bertelson CJ, Monaco AP, Feener C, Kunkel LM. Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals. Cell. 1987;50:509-517. PUBMED
10. Gitschier J, Wood WI, Tuddenham EGD. Detection and sequence of mutations in the factor VIII gene of haemophiliacs. Nature. 1985;315:427-430. PUBMED
11. Wallace MR, Marchuk DA, Andersen LB, et al. Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients. Science. 1990:249:181-186. FREE FULL TEXT
12. HD Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell. 1993;72:971-983. PUBMED
13. Chang JC, Kan YW. A sensitive new prenatal test for sickle-cell anemia. N Engl J Med. 1982;307:30-32. PUBMED
14. Lemna WK, Feldman GL, Kerem B, et al. Mutation analysis for heterozygote detection and the prenatal diagnosis of cystic fibrosis. N Engl J Med. 1990;322:291-296. ABSTRACT
15. Multicenter Study Group. Diagnosis of Duchenne and Becker muscular dystrophies by polymerase chain reaction: a multicenter study. JAMA. 1992;267:2609-2615. FREE FULL TEXT
16. Kogan SC, Doherty M, Gitschier J. An improved method for prenatal diagnosis of genetic diseases by analysis of amplified DNA sequences: application to hemophilia A. N Engl J Med. 1987;317:985-990. ABSTRACT
17. Tsipouras P, Del Mastro R, Sarfarazi M, et al. Genetic linkage of the Marfan syndrome, ectopia lentis, and congenital contractural arachnodactyly to the fibrillin genes on chromosomes 15 and 5. N Engl J Med. 1992;326:905-909. ABSTRACT
18. Reeders ST, Zerres K, Gal A, et al. Prenatal diagnosis of autosomal dominant polycystic kidney disease with a DNA probe. Lancet. 1986;2:6-7. PUBMED
19. US Depts of Health and Human Services and Energy. Understanding Our Genetic Inheritance: The US Human Genome Project: The First Five Years FY 1991-1995. Washington, DC: US Depts of Health and Human Services and Energy; 1990:1.
20. Juengst ET. The human genome project and bioethics. Kennedy Inst Ethics J. 1991;1:71-74. PUBMED
21. Lappe M. Ethical issues in manipulating the human germ line. J Med Philos. 1991;16:621-639. PUBMED
22. Nolan K, Swenson S. New tools, new dilemmas: genetic frontiers. Hastings Cent Rep. 1988;18(5):40-46. PUBMED
23. American Medical Association Council on Ethical and Judicial Affairs. Use of genetic testing by employers. JAMA. 1991;266:1827-1830. FREE FULL TEXT
24. Eisenbarth GS. Type 1 diabetes mellitus: a chronic autoimmune disease. N Engl J Med. 1986;314:1360-1368. PUBMED
25. Karathanasis SK, Vassilis IZ, Breslow JL. A DNA insertion in the apolipoprotein A-l gene of patients with premature atherosclerosis. Nature. 1983;305:823-825. PUBMED
26. Bodmer WF, Bailey CJ, Bodmer J, et al. Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature. 1987;328:614-616. PUBMED
27. Hall JM, Lee MK, Newman B, et al. Linkage of early-onset familial breast cancer to chromosome 17q21. Science. 1990;250:1684-1689. FREE FULL TEXT
28. Egeland JA, Gerhard DS, Pauls DL, et al. Bipolar affective disorders linked to DNA markers on chromosome 11. Nature. 1987;325:783-787. PUBMED
29. Reeders ST, Breuning MH, Davies HE, et al. A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16. Nature. 1985;317:542-544. PUBMED
30. Murrell J, Farlow M, Ghetti B, Benson MD. A mutation in the amyloid precursor protein associated with Alzheimer's disease. Science. 1991;254:97-99. FREE FULL TEXT
31. Collins FS. Medical and ethical consequences of the human genome project. J Clin Ethics. 1991;2:260-267. PUBMED
32. Clarke A. Is non-directive genetic counselling possible? Lancet. 1991;338:998-1001. PUBMED
33. Post SG, Botkin JR, Whitehouse P. Selective abortion for familial Alzheimer disease? Obstet Gynecol. 1992;79:794-798. PUBMED
34. Anderson WF. Human gene therapy: why draw a line? J Med Philos. 1989;14:681-693. FREE FULL TEXT
35. Wertz DC, Fletcher JC, ed. Ethics and Human Genetics: A Cross-Cultural Perspective. New York, NY: Springer-Verlag NY Inc; 1989:34.
36. Elsas LJ II. A clinical approach to legal and ethical problems in human genetics. Emory Law J. 1990;39:811-853. PUBMED
37. Wertz DC, Fletcher JC. Fatal knowledge? prenatal diagnosis and sex selection. Hastings Cent Rep. 1989;19(3):21-27. PUBMED
38. Botkin JR. Prenatal screening: professional standards and the limits of parental choice. Obstet Gynecol. 1990;75:875-880. PUBMED
39. Selypes A, Lorencz R. A noninvasive method for determination of the sex and karyotype of the fetus from the maternal blood. Hum Genet. 1988;79:357-359. PUBMED
40. Elias S, Price J, Dockter M, et al. First trimester prenatal diagnosis of trisomy 21 in fetal cells from maternal blood. Lancet. 1992;340:1033. PUBMED
41. Zimmerman BK. Human germ-line therapy: the case for its development and use. J Med Philos. 1991;16:593-612. FREE FULL TEXT
42. A report from Germany: an extract from 'Prospects and risks of gene technology: the report of the Enquete Commission to the Bundestag of the Federal Republic of Germany.' Bioethics. 1988;2:254-263. PUBMED
43. Munson R, Davis LH. Germ-line gene therapy and the medical imperative. Kennedy Inst Ethics J. 1992;2:137-158. PUBMED
44. Berman V Allan, 404 A.2d 8 (NJ 1979).
45. Roe v Wade, 410 US 113 (1973).